Medical and biological safety assessment of genetically modified maize event MIR604

There are presented the results of genotoxicologic, immunologic and allergologic examinations which were conducted within the framework of integrated medical and biological assessment of genetically modified rootworm Diabrotica spp.-protected maize event MIR604. Analysis of damages of DNA and struct...

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Bibliographic Details
Published inVoprosy pitaniia Vol. 78; no. 2; p. 33
Main Authors Tyshko, N V, Britsina, M V, Gmoshinskiĭ, I V, Zhanataev, A K, Zakharova, N S, Zorin, S N, Mazo, V K, Ozeretskovskaia, M N, Semenov, B F
Format Journal Article
LanguageRussian
Published Russia (Federation) 2009
Subjects
Anaphylaxis - etiology
Anaphylaxis - immunology
Animals
Bone Marrow Cells - metabolism
Bone Marrow Cells - ultrastructure
Chromosome Aberrations
Colon - metabolism
Comet Assay
DNA Damage
Food Analysis - methods
Food Hypersensitivity - etiology
Food, Genetically Modified - adverse effects
Food, Genetically Modified - standards
Food, Genetically Modified - toxicity
Hypersensitivity, Delayed - etiology
Hypersensitivity, Delayed - immunology
Liver - metabolism
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Ovalbumin
Plants, Genetically Modified - adverse effects
Plants, Genetically Modified - toxicity
Rats
Rats, Wistar
Species Specificity
Toxicity Tests
Zea mays - adverse effects
Zea mays - genetics
Zea mays - standards
Zea mays - toxicity
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Summary:There are presented the results of genotoxicologic, immunologic and allergologic examinations which were conducted within the framework of integrated medical and biological assessment of genetically modified rootworm Diabrotica spp.-protected maize event MIR604. Analysis of damages of DNA and structural chromosome aberrations, assessment of the allergenic potential and immunoreactive properties has not confirmed any genotoxic, allergenic and immunotoxic effect of maize event MIR604.
ISSN:0042-8833