Central vein occlusion in a patient using interferon and ribavirin: case report

Interferon and ribavirin are medications widely used in the treatment of some systemic diseases, mainly hepatitis C. Ribavirin when associated with interferon increases the rate of success of this treatment. There are about 170 million patients with chronic hepatitis C in the world, many in use of t...

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Bibliographic Details
Published inArquivos brasileiros de oftalmologia Vol. 69; no. 4; p. 601
Main Authors Helal, Jr, John, Zacharias, Leandro Cabral, de Alencar, Luciana Malta
Format Journal Article
LanguagePortuguese
Published Brazil 01.07.2006
Subjects
Antiviral Agents - adverse effects
Drug Therapy, Combination
Female
Hepatitis C, Chronic - drug therapy
Humans
Interferon-alpha - adverse effects
Middle Aged
Recombinant Proteins
Retinal Hemorrhage - chemically induced
Retinal Hemorrhage - diagnosis
Retinal Vein Occlusion - chemically induced
Retinal Vein Occlusion - diagnosis
Ribavirin - adverse effects
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Summary:Interferon and ribavirin are medications widely used in the treatment of some systemic diseases, mainly hepatitis C. Ribavirin when associated with interferon increases the rate of success of this treatment. There are about 170 million patients with chronic hepatitis C in the world, many in use of these medications. The classic associated retinopathy is described as cotton wool exudates and hemorrhages. Since the first reports, several different ocular disturbances were described in association with interferon. The present case shows a patient whose right eye presented with central retinal vein occlusion and whose left eye presented the typical findings of hemorrhages; prompt resolution after the medications were discontinued.
ISSN:0004-2749