Photodynamic therapy for treatment of choroidal neovascularization

• Published in: Archivos de la Sociedad Española de Oftalmología Vol. 79; no. 12; pp. 609 - 615
• Main Authors: Pérez Oliván, S, Torrón Fernández-Blanco, C, Ferrer Novella, E, Ruiz-Moreno, O, Honrubia, F M
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.12.2004
• Subjects: Aged; Choroidal Neovascularization - drug therapy; Choroidal Neovascularization - etiology; Female; Humans; Macular Degeneration - complications; Male; Myopia - complications; Photochemotherapy
• ISSN: 0365-6691

To evaluate the efficacy of photodynamic therapy with photodynamic therapy (PDT) in the management of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) and myopia. 102 eyes with subfoveal or yuxtafoveal CNV underwent visual acuity (VA) testing, ophthalmic examination, and fluorescein angiography. Retreatment of persistent CNV was done after three months. CNV was caused by AMD in 75.5% of patients, pathologic myopia in 24.5%. Follow up ranged from 9 to 33 months (mean: 15.94 months). 88% of CNV caused by pathologic myopia was classic and 40% was in lesions caused by AMD. CNV survival was shorter in lesions caused by pathologic myopia with a significant difference (p=0.0018). VA improved in 48% of lesions caused by pathologic myopia and in 28.6% of lesions caused by AMD. We did not observe any severe complication caused by PDT. PDT is a moderately effective treatment without complications in treating subfoveal CNV.