Use of cholinesterase inhibitors in Alzheimer disease

According to the cholinergic theory of Alzheimer's disease, the cognitive failure depends on a deficit in acetylcholine. The study reported above examines the efficacy and tolerability of cholinesterase inhibitors, such as tetrahydroamino acridine (THA), for the management of this pathology.

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Bibliographic Details
Published inClinica terapeutica Vol. 143; no. 6; p. 549
Main Authors Sampalmieri, M, Troiani, M P, Servi, M
Format Journal Article
LanguageItalian
Published Italy 01.12.1993
Subjects
Acetylcholine - deficiency
Alzheimer Disease - drug therapy
Alzheimer Disease - metabolism
Cholinesterase Inhibitors - administration & dosage
Cognition Disorders - drug therapy
Cognition Disorders - metabolism
Female
Humans
Male
Tacrine - administration & dosage
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Summary:According to the cholinergic theory of Alzheimer's disease, the cognitive failure depends on a deficit in acetylcholine. The study reported above examines the efficacy and tolerability of cholinesterase inhibitors, such as tetrahydroamino acridine (THA), for the management of this pathology.
ISSN:0009-9074