Clinical trials of various glaucoma drugs acting on the adrenergic system (author's transl)

The authors summarize findings in a clinical trial of the betablockers Timolol and Metoprolol, as well as the effectiveness of various concentration of the combination preparation Guanethidine-Adrenaline. In the trial Timolol proved to be the almost ideal drug for glaucoma therapy. However, as a pre...

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Bibliographic Details
Published inKlinische Monatsblätter für Augenheilkunde Vol. 176; no. 4; p. 555
Main Authors Urner-Bloch, U, Bucheli, J, Eltz, H, Gloor, B, Aeschlimann, J
Format Journal Article
LanguageGerman
Published Germany 01.04.1980
Subjects
Adrenergic beta-Antagonists - therapeutic use
Clinical Trials as Topic
Drug Combinations
Epinephrine - therapeutic use
Glaucoma - drug therapy
Guanethidine - therapeutic use
Humans
Metoprolol - therapeutic use
Timolol - therapeutic use
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Summary:The authors summarize findings in a clinical trial of the betablockers Timolol and Metoprolol, as well as the effectiveness of various concentration of the combination preparation Guanethidine-Adrenaline. In the trial Timolol proved to be the almost ideal drug for glaucoma therapy. However, as a pressure-lowering agent the guanethidine-epinephrine combination is more effective. Metroprolol, which is a pure beta 1-blocker, is probably preferable to Timolol in asthmatic patients.
ISSN:0023-2165