Comparison of intensified traditional insulin therapy and micropump therapy in pregnant women with type 1 diabetes mellitus

Ten pregnant women, affected by type I diabetes mellitus, observed for the first time during the II-III month of pregnancy, were examined. These patients were divided in two groups at random: group A underwent continuous subcutaneous insulin infusion with micropump CPI 9100 Lilly; group B underwent...

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Bibliographic Details
Published inMinerva medica Vol. 77; no. 17; p. 657
Main Authors Botta, R M, Sinagra, D, Angelico, M C, Bompiani, G D
Format Journal Article
LanguageItalian
Published Italy 21.04.1986
Subjects
Adult
Birth Weight
Blood Glucose - analysis
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - diet therapy
Diabetes Mellitus, Type 1 - drug therapy
Female
Fetal Diseases - epidemiology
Humans
Infant, Newborn
Insulin - administration & dosage
Insulin Infusion Systems
Pregnancy
Pregnancy in Diabetics - blood
Pregnancy in Diabetics - diet therapy
Pregnancy in Diabetics - drug therapy
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Summary:Ten pregnant women, affected by type I diabetes mellitus, observed for the first time during the II-III month of pregnancy, were examined. These patients were divided in two groups at random: group A underwent continuous subcutaneous insulin infusion with micropump CPI 9100 Lilly; group B underwent intensified insulin therapy with three daily doses of MC rapid insulin, two of which associated with MC intermediate insulin. All the patients were able to monitor their own blood glucose levels at home by means of reactive strips and reflectometer. In both the groups the mean glycemic values during fast and two hours after meals, and the eventual presence of urinary keton bodies and hypoglycemic crisis were evaluated during the course of pregnancy: these parameters turned out to be identical in the two groups. The increased need of insulin, the maternal body weight gain, the week and mode of delivery, the neonatal weight and the maternal and fetal complications also turned out to be identical in the two groups. To conclude, a good maternal metabolic control can be obtained either with the intensified conventional insulin therapy of with micropumps, if the patients, being properly instructed, are responsible for the monitoring of their own blood glucose levels at home.
ISSN:0026-4806