Malignant tumors of the genitalia in girls

• Published in: Voprosy onkologij Vol. 32; no. 1; p. 74
• Main Authors: Bokhman, Ia V, Nechaeva, I D, Maksimov, S Ia, Kutusheva, G F, Kolygin, B A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 1986
• Subjects: Adolescent; Age Factors; Child; Child, Preschool; Combined Modality Therapy; Female; Genital Neoplasms, Female - diagnosis; Genital Neoplasms, Female - epidemiology; Genital Neoplasms, Female - therapy; Humans; Infant; Infant, Newborn; Ovarian Neoplasms - diagnosis; Ovarian Neoplasms - epidemiology; Ovarian Neoplasms - therapy; Prognosis; Risk; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - epidemiology; Uterine Cervical Neoplasms - therapy; Vaginal Neoplasms - diagnosis; Vaginal Neoplasms - epidemiology; Vaginal Neoplasms - therapy; Vulvar Neoplasms - diagnosis; Vulvar Neoplasms - epidemiology; Vulvar Neoplasms - therapy
• ISSN: 0507-3758

A review of the literature and analysis of 40 cases of genital malignancies girls are presented. 31 patients had ovarian tumor, 2--cervical, 4--vaginal and 3--tumor of the vulva. Most embryonal rhabdomyosarcoma of the vagina or the vulva occurred in patients under 4 whereas ovarian neoplasms (mostly germ and sex cord tumors) were observed at prepubertal and pubertal age. Early dissemination and unfavorable prognosis were typical of rhabdomyosarcoma of the vagina and vulva. Stage I dysgerminoma and granulosa cell tumor usually make the case for sparing surgery whereas stage II and III malignancies--for a radical one, irrespective of histological pattern. Prognosis is better when surgery is supplemented with individually-tailored chemotherapy.