Lomir in the treatment of arterial hypertension after angioplastic surgery

Isradipine (lomir) is a new highly selective arteriolar vasodilator of the dihydropyridine group, characterized by a slight cardiodepressive effect. The drug effect on the central hemodynamics and oxygen transport was studied after cardiovascular surgery. Arterial pressure and total peripheral vascu...

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Bibliographic Details
Published inAnesteziologiia i reanimatologiia no. 2; p. 65
Main Authors Lebedeva, R N, Eremenko, A A, Ziuliaeva, T P, Mikhaĭlov, Iu M, Matiunin, A V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.03.1996
Subjects
Adult
Aged
Antihypertensive Agents - therapeutic use
Aorta, Abdominal - surgery
Assisted Circulation
Blood Vessel Prosthesis
Calcium Channel Blockers - therapeutic use
Cardiac Surgical Procedures
Carotid Arteries - surgery
Coronary Artery Bypass
Endarterectomy
Female
Femoral Artery - surgery
Heart Arrest, Induced
Heart Valve Prosthesis
Hemodynamics
Humans
Hypertension - drug therapy
Hypertension - physiopathology
Isradipine - therapeutic use
Male
Middle Aged
Mitral Valve - surgery
Postoperative Complications
Thoracic Arteries - surgery
Vasodilator Agents - therapeutic use
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Summary:Isradipine (lomir) is a new highly selective arteriolar vasodilator of the dihydropyridine group, characterized by a slight cardiodepressive effect. The drug effect on the central hemodynamics and oxygen transport was studied after cardiovascular surgery. Arterial pressure and total peripheral vascular resistance were reliably reduced at the peak of the drug action, as was the left-ventricular stroke work and oxygen consumption. A tendency to increase of cardiac output and cardiac index was observed. Pulmonary vascular resistance and pressure in the pulmonary artery did not reliably change. The drug increased the intrapulmonary shunt.
ISSN:0201-7563