Cyclic analogs of angiotensin with depressor and histamine-liberating activity

The synthesis and biological properties of 10 angiotensin cyclic analogues are described. These compounds exhibit prolong depressor effects and act as potent histamine-releasing agents.

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Bibliographic Details
Published inBioorganicheskaia khimiia Vol. 12; no. 8; p. 1118
Main Authors Antsans, Iu E, Bisenietse, D A, Mshliakova, N V, Porunkevich, E A, Ratkevich, M P
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.08.1986
Subjects
Angiotensin II - analogs & derivatives
Angiotensin II - chemical synthesis
Angiotensin II - pharmacology
Animals
Antihypertensive Agents - chemical synthesis
Histamine Release - drug effects
Peptides, Cyclic - chemical synthesis
Peptides, Cyclic - pharmacology
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Summary:The synthesis and biological properties of 10 angiotensin cyclic analogues are described. These compounds exhibit prolong depressor effects and act as potent histamine-releasing agents.
ISSN:0132-3423