The TRH test using the Bulgarian preparation Protilerin in the diagnosis of hyperthyroidism

The stimulation test--TRH test was carried out with the Bulgarian drug "Protilerin" in 63 patients (Basedow's disease--53 patients, basedoid goiter--5 patients, infiltrative ophthalmopathy--5 patients) and in 20 healthy controls. The healthy controls showed normal reaction to the stim...

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Bibliographic Details
Published inVutreshni bolesti Vol. 28; no. 5; p. 30
Main Authors Manolov, D, Zakharieva, B, Lazarov, G, Manov, A, Vŭrbanov, V
Format Journal Article
LanguageBulgarian
Published Bulgaria 1989
Subjects
Adult
Drug Evaluation
Euthyroid Sick Syndromes - diagnosis
Eye Diseases - diagnosis
Female
Graves Disease - diagnosis
Humans
Hyperthyroidism - diagnosis
Male
Thyrotropin-Releasing Hormone
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Summary:The stimulation test--TRH test was carried out with the Bulgarian drug "Protilerin" in 63 patients (Basedow's disease--53 patients, basedoid goiter--5 patients, infiltrative ophthalmopathy--5 patients) and in 20 healthy controls. The healthy controls showed normal reaction to the stimulation. All patients with hyperthyroidism showed a suppressed response to the stimulation. In two of the patients with euthyroid infiltrative ophthalmopathy the response was similar to that of the healthy controls. The Bulgarian drug Protilerin is suitable for the performance of the TRH test in the diagnosis of hyperthyroidism.
ISSN:0506-2772