Incidence of HBAg in various liver diseases (comparison between radioimmunologic methods and methods of passive hemagglutination)

In order to determine the frequency of HBAg in Campania, the AA. have examined a large number of liver patients accurately selected and subdivided in five classes: acute hepatitis, chronic hepatitis, cirrhosis, hepatocarcinoma, and various liver diseases. They have employed radioimmuno assays (RIA)...

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Published inQuaderni Sclavo di diagnostica clinica e di laboratorio Vol. 11; no. 2; p. 561
Main Authors Claar, G M, Alvaro, M C, Ascione, A, De Bellis, G, Sodano, S, Varone, G L
Format Journal Article
LanguageItalian
Published Italy 01.06.1975
Subjects
Antibody Formation
Chronic Disease
Hemagglutination Tests
Hepatitis A - immunology
Hepatitis B - immunology
Hepatitis B Antigens - isolation & purification
Humans
Liver Cirrhosis - immunology
Liver Diseases - immunology
Liver Neoplasms - immunology
Radioimmunoassay
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Summary:In order to determine the frequency of HBAg in Campania, the AA. have examined a large number of liver patients accurately selected and subdivided in five classes: acute hepatitis, chronic hepatitis, cirrhosis, hepatocarcinoma, and various liver diseases. They have employed radioimmuno assays (RIA) with human and guinea pig antibodies and techniques of passive haemoagglutination. The percentage of HBAg positive subjects among the various classes of liver diseases determined with these techniques is significantly higher than the one remarked by the AA. in 1972 by electrosineresis on the same population. Both RIA and haemoagglutination supply satisfactory results, although for haemoagglutination one must remember the subjectiveness of the reading.
ISSN:0033-4979