Impact of specific antituberculosis therapy on gastrointestinal tract in children

Forty eight children aged 3 to 14 years treated at hospital for various tuberculous abnormalities were examined. The findings suggest that the use of antituberculosis agents in children with normal acid and pepsin production failed to have a noticeable effect on the gastrointestinal tract. Moreover,...

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Bibliographic Details
Published inProblemy tuberkuleza no. 2; p. 22
Main Authors Paĭkov, V L, Korol', O I, Kravchenko, L I, Bandurina, T Iu, Noskova, O M
Format Journal Article
LanguageRussian
Published Russia (Federation) 1998
Subjects
Adolescent
Antitubercular Agents - therapeutic use
Child
Child, Preschool
Digestive System - drug effects
Follow-Up Studies
Gastric Juice - drug effects
Gastric Juice - secretion
Gastric Mucosa - drug effects
Gastric Mucosa - secretion
Humans
Pepsin A - drug effects
Pepsin A - secretion
Tuberculosis - drug therapy
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Summary:Forty eight children aged 3 to 14 years treated at hospital for various tuberculous abnormalities were examined. The findings suggest that the use of antituberculosis agents in children with normal acid and pepsin production failed to have a noticeable effect on the gastrointestinal tract. Moreover, the 6-month use of highly and moderately effective antituberculosis agents produced no effect on the aggressive properties of gastric juice. It is necessary to prescribe enveloping and mucus-forming agents to reduce the potential side effect of tuberculostatic therapy.
ISSN:0032-9533