DNA complexes with synthetic oligopeptides: a model for studying the regularity of DNA compactization in vivo

The electron microscopic data on compactization of DNA at interaction with the synthetic oligopeptides having the trend of beta-structures formation in solutions are summarized. The new types of intramolecular and intermolecular compact structures are described in brief. Sequence of compactization p...

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Bibliographic Details
Published inMolekulârnaâ genetika, mikrobiologiâ i virusologiâ no. 1; p. 3
Main Authors Vengerov, Iu Iu, Semenov, T E
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.1989
Subjects
DNA
Nucleic Acid Conformation
Oligopeptides
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Summary:The electron microscopic data on compactization of DNA at interaction with the synthetic oligopeptides having the trend of beta-structures formation in solutions are summarized. The new types of intramolecular and intermolecular compact structures are described in brief. Sequence of compactization process steps is discussed, the models of DNA packaging in the structures are presented. On the basis of the data presented the general principles of arrangement of the described compact structures are formulated, the mechanisms are proposed for formation of different types of compact particles on the final stage of the process of DNA condensation. Some processes of the genetic material compactization in vivo are discussed in which the proposed mechanisms for compact structures formation may have realization.
ISSN:0208-0613