Neuroblastoma with bone marrow invasion. A multicenter study. Work Group of the Spanish Society of Pediatric Surgery

By means of a retrospective study made of multiple centres, it was aimed to determine which variables could be influential at the moment of diagnosis in the prognostic of patients suffering neuroblastoma and medullary bone affection. Fifty four cases of patients belonging to a total of ten hospital...

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Bibliographic Details
Published inCirugía pediátrica Vol. 7; no. 4; p. 164
Main Authors Jiménez Alvarez, C, Bregante Ucedo, J I, Costa Borrás, E, Martínez Ibáñez, V, Mulet Ferragut, J F, Obiols Arderius, P, Queizán de la Fuente, A, Rollán Villamarín, V, Sainz Samitier, A, Torres Piedra, C
Format Journal Article
LanguageSpanish
Published Spain 01.10.1994
Subjects
Abdominal Neoplasms - mortality
Abdominal Neoplasms - pathology
Abdominal Neoplasms - therapy
Adrenal Gland Neoplasms - mortality
Adrenal Gland Neoplasms - pathology
Adrenal Gland Neoplasms - therapy
Bone Marrow - pathology
Bone Neoplasms - secondary
Child
Child, Preschool
Female
Humans
Infant
Male
Mediastinal Neoplasms - mortality
Mediastinal Neoplasms - pathology
Mediastinal Neoplasms - therapy
Neoplasm Invasiveness
Neoplasm Metastasis
Neuroblastoma - mortality
Neuroblastoma - pathology
Neuroblastoma - therapy
Retrospective Studies
Time Factors
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Summary:By means of a retrospective study made of multiple centres, it was aimed to determine which variables could be influential at the moment of diagnosis in the prognostic of patients suffering neuroblastoma and medullary bone affection. Fifty four cases of patients belonging to a total of ten hospital centers have been revised in a period of five years. The ages under study spanned from three months to eight years of age (mean = 2.83 years). For the analysis of the patients, they were divided into two groups: one being composed of the deceased patients and the other of the surviving. The deceased patients were of a more advanced age, the delay in the diagnosis was greater, the primitive tumor was found to be more frequently located in the adrenal glands, the metastasis appeared more readily in multiples, and the effectiveness of the treatment was less, resulting in lower cases of remission and a less radical surgery. The only difference with respect to other publications is that in the case of surviving patients, the number of cases of enolase and ferritin is more frequently pathological.
ISSN:0214-1221