Extractive polarographic method of controlling the stereospecific hydrolysis of N-acylated derivatives of amino acid racemates

• Published in: Antibiotiki Vol. 27; no. 1; p. 6
• Main Authors: Satarova, D E, Skvortsova, E E, Nys, P S, Korchagin, V B, Savitskaia, E M
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.01.1982
• Subjects: Acylation; Amino Acids - analysis; Amino Acids - isolation & purification; Glycine - analogs & derivatives; Glycine - analysis; Glycine - isolation & purification; Hydrolysis; Mathematics; Polarography - methods; Stereoisomerism

The equilibrium distribution of acetyl-D-phenylglycine prepared with stereospecific hydrolysis of acetyl-D,L-phenylglycine (Ac-D,L-PhG) was studied in a two-phase system of benzyl alcohol-1N HCl solution. It was found that the distribution coefficient of Ac-D-PhG did not practically depend on its co...