Reactions of the lymphoid organs of the rat to acute stress in hypokinesia

Female rats long exposed to hypokinesia were then subjected to an acute stress. In this situation the thymus and spleen were examined. The destructive process in the thymus increased in spite of its hypoplasia. This can be attributed to a greater production of corticosteroids by the adrenals caused...

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Bibliographic Details
Published inKosmicheskaia biologiia i aviakosmicheskaia meditsina Vol. 18; no. 5; p. 50
Main Author Vorotnikova, E V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.09.1984
Subjects
Acute Disease
Animals
Atrophy
Female
Humans
Movement Disorders - pathology
Rats
Restraint, Physical
Spleen - pathology
Stress, Psychological - pathology
Thymus Gland - pathology
Time Factors
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Summary:Female rats long exposed to hypokinesia were then subjected to an acute stress. In this situation the thymus and spleen were examined. The destructive process in the thymus increased in spite of its hypoplasia. This can be attributed to a greater production of corticosteroids by the adrenals caused by the chronic stress. At the same time the white pulp of the spleen decreased insignificantly because it contained no lymphocytes capable to migrate by the time of the acute stress-effect. It is concluded that enhanced destruction of lymphocytes in the thymus in response to an acute stress can be regarded as a diagnostic test of the adrenal state during a chronic stress-effect, including hypokinesia.
ISSN:0321-5040