Na+ and K+ ion transport across the human erythrocyte membrane during the formation of nystatin channels under in-vitro conditions: the characteristics and an analysis of the processes

The kinetic properties (the spontaneous lysis velocity, the time of achievement, and the concentration level of the stationary stage) are shown to be strongly different, while the human erythrocytes are resuspended in various salt media. The analysis of Na+ and K+ concentrations, under the effect of...

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Bibliographic Details
Published inT͡S︡itologii͡a Vol. 36; no. 5; p. 427
Main Authors Borisov, Iu A, Soboleva, O Iu, Suglobova, E D, Fedorovich, E E
Format Journal Article
LanguageRussian
Published Russia (Federation) 1994
Subjects
Biological Transport, Active - drug effects
Diffusion
Dose-Response Relationship, Drug
Erythrocyte Membrane - drug effects
Erythrocyte Membrane - metabolism
Furosemide - pharmacology
Humans
In Vitro Techniques
Nystatin - pharmacology
Ouabain - pharmacology
Potassium - blood
Potassium Channels - drug effects
Potassium Channels - metabolism
Sodium - blood
Sodium Channels - drug effects
Sodium Channels - metabolism
Sodium-Potassium-Exchanging ATPase - blood
Time Factors
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Summary:The kinetic properties (the spontaneous lysis velocity, the time of achievement, and the concentration level of the stationary stage) are shown to be strongly different, while the human erythrocytes are resuspended in various salt media. The analysis of Na+ and K+ concentrations, under the effect of a polyene antibiotic nistatin, on the human erythrocytes as an integral kinetic function of time is carried out. The processes engaged in this kinetic function are characterized.
ISSN:0041-3771