Effect of glutamate on the trace element content in the mitochondria of the liver, heart and kidneys of rats with acute and chronic hypoxia

Acute hypoxia ("height" 8000 metres, 60 minutes) decreases concentration of copper, zinc and magnesium in mitochondria of the liver, kidney, that of copper and magnesium decreases in the heart. Chronic hypoxia ("height" 6000 metres, 6 hours a day for 2 weeks) also causes a decrea...

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Bibliographic Details
Published inUkrains'kyi biokhimichnyi zhurnal Vol. 48; no. 5; p. 559
Main Authors Glotov, N A, Vul'fson, A M
Format Journal Article
LanguageRussian
Published Ukraine 01.09.1976
Subjects
Acute Disease
Animals
Chronic Disease
Copper - metabolism
Glutamates - pharmacology
Hypoxia - metabolism
Kidney - metabolism
Magnesium - metabolism
Male
Mitochondria - drug effects
Mitochondria - metabolism
Mitochondria, Liver - drug effects
Mitochondria, Muscle - drug effects
Myocardium - metabolism
Rats
Trace Elements - metabolism
Zinc - metabolism
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Summary:Acute hypoxia ("height" 8000 metres, 60 minutes) decreases concentration of copper, zinc and magnesium in mitochondria of the liver, kidney, that of copper and magnesium decreases in the heart. Chronic hypoxia ("height" 6000 metres, 6 hours a day for 2 weeks) also causes a decrease in the concentration of copper, zinc and magnesium in mitochondria of the liver, kidney and that of copper and magnesium--in the heart. Glutamic acid (acute and chronic hypoxia) increases the level of copper, zinc and magnesium in mitochondria of the liver, heart and kidney of albino rats which is close to its values in the normal animals.
ISSN:0041-610X