Reversibility of severe digitoxin poisoning with antidigoxin antibodies

• Published in: Annales de médecine interne Vol. 134; no. 6; p. 555
• Main Authors: Domart, Y, Bismuth, C, Pontal, P G, Scherrmann, J M, Baud, F, Muszynski, J, Elkhouly, M, Fournier, P E
• Format: Journal Article
• Language: French
• Published: France 1983
• Subjects: Aged; Digitoxin - blood; Digitoxin - poisoning; Digoxin - immunology; Electrocardiography; Humans; Immunoglobulin Fab Fragments; Male

We report a case of severe digitoxin poisoning treated at the stage of ventricular fibrillation by infusion of FAB antidigoxin fragments with low in vitro covering properties. There were no side effects. The possibility of rapidly reversing the prognosis will permit the use of specific FAB fragments...