Clinical tolerance of hemodialysis sessions in children. Comparison of bicarbonate and acetate baths

• Published in: Nephrologie Vol. 4; no. 4-5; p. 201
• Main Authors: Pierre, G, Landthaler, G
• Format: Journal Article
• Language: French
• Published: Switzerland 1983
• Subjects: Acetates - adverse effects; Age Factors; Bicarbonates - adverse effects; Child; Child, Preschool; Drug Tolerance; Humans; Renal Dialysis - adverse effects; Vomiting - chemically induced
• ISSN: 0250-4960

Hemodialysis tolerance was studied in 3 children during periods of respectively 6, 7 and 9 months comparing bicarbonate (B) versus acetate (A) with equivalent number of sessions. Parameters used for tolerance in these three cases were: hypotensive bouts, solutes perfused during sessions, mean alimentary intake, vomiting, headache, abdominal pain and benzodiazepine prescriptions, taking account of ultrafiltration and dry weight variations during this periods. Results with bicarbonate are following: Obs. n degrees 1 (11 year old female, cystinosis, A: 38 sessions, B: 44 sessions): significant improvement of hypotension episodes and reduction of solutes perfused (p less than 0,05), of vomiting (p less than 0,001), and increase of mean alimentary intake (p less than 0,001). Obs. n degrees 2 (11 year old male, glomerular nephropathy, A: 25 sessions, B: 27 sessions): non significant improvement of hypotension episodes, but improvement for mean alimentary intake (p less than 0,01). Obs. n degrees 3 (4 year old male, uropathy with renal hypoplasia): no significant improvement, but for this child A hemodialysis tolerance was better than for both others. B hemodialysis seems a good alternative for children with A intolerance.