An electron microscopic and radioautographic study of bronchoalveolar lavage in chronic inflammation of the lungs under the effects of helium-neon laser

• Published in: Biulleten' eksperimental'noi biologii i meditsiny Vol. 108; no. 7; p. 117
• Main Authors: Nepomniashchikh, L M, Polosukhin, V V, Nepomniashchikh, G I
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.07.1989
• Subjects: Adult; Autoradiography; Bronchoalveolar Lavage Fluid - cytology; DNA - biosynthesis; Humans; Laser Therapy; Leukocyte Count; Lung - pathology; Lung Diseases - radiotherapy; Macrophages; Male; Microscopy, Electron; Middle Aged; Neutrophils; RNA - biosynthesis
• ISSN: 0365-9615

136 samples of bronchoalveolar lavage (BAL) from 45 men-patients with chronic inflammatory processes of lung were studied in course of endobronchial laser influence. It was shown, that considerable quantitative and qualitative changes in cell composition of BAL-fluid were resulted from helium-neon laser influence, these are the percentage increase of macrophage amount and the decrease of neutrophil numbers. By use of radioautographic analysis the stimulation of metabolic and proliferative reactions (on the level of RNA and DNA syntheses) of alveolar macrophages under laser influence was found. On the basis of morphological changes of cells in respiratory compartment of the lung it was concluded that clinical effect of laser treatment of chronic inflammatory processes in the lung was conditioned by stimulation of regenerative-plastic reactions.