An electron microscopic and radioautographic study of bronchoalveolar lavage in chronic inflammation of the lungs under the effects of helium-neon laser

136 samples of bronchoalveolar lavage (BAL) from 45 men-patients with chronic inflammatory processes of lung were studied in course of endobronchial laser influence. It was shown, that considerable quantitative and qualitative changes in cell composition of BAL-fluid were resulted from helium-neon l...

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Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 108; no. 7; p. 117
Main Authors Nepomniashchikh, L M, Polosukhin, V V, Nepomniashchikh, G I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1989
Subjects
Adult
Autoradiography
Bronchoalveolar Lavage Fluid - cytology
DNA - biosynthesis
Humans
Laser Therapy
Leukocyte Count
Lung - pathology
Lung Diseases - radiotherapy
Macrophages
Male
Microscopy, Electron
Middle Aged
Neutrophils
RNA - biosynthesis
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Summary:136 samples of bronchoalveolar lavage (BAL) from 45 men-patients with chronic inflammatory processes of lung were studied in course of endobronchial laser influence. It was shown, that considerable quantitative and qualitative changes in cell composition of BAL-fluid were resulted from helium-neon laser influence, these are the percentage increase of macrophage amount and the decrease of neutrophil numbers. By use of radioautographic analysis the stimulation of metabolic and proliferative reactions (on the level of RNA and DNA syntheses) of alveolar macrophages under laser influence was found. On the basis of morphological changes of cells in respiratory compartment of the lung it was concluded that clinical effect of laser treatment of chronic inflammatory processes in the lung was conditioned by stimulation of regenerative-plastic reactions.
ISSN:0365-9615