Availability of propylphenazocine from suppositories. 1. In vitro bioavailability

Comparing examinations of the in-vitro availability of propyphenazone from suppositories of different fat bases (Rosupol U, Witepsol H 15) did not display any differences in the release behaviour. Compared with propyphenazone preparations, aminophenazone suppositories of the same concentration exhib...

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Bibliographic Details
Published inPharmazie Vol. 40; no. 10; p. 718
Main Authors Bornschein, M, Voigt, R, Hoffmann, K
Format Journal Article
LanguageGerman
Published Germany 01.10.1985
Subjects
Antipyrine - administration & dosage
Antipyrine - analogs & derivatives
Antipyrine - metabolism
Biological Availability
Chemical Phenomena
Chemistry, Physical
In Vitro Techniques
Solubility
Suppositories
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Summary:Comparing examinations of the in-vitro availability of propyphenazone from suppositories of different fat bases (Rosupol U, Witepsol H 15) did not display any differences in the release behaviour. Compared with propyphenazone preparations, aminophenazone suppositories of the same concentration exhibit a significantly increased in-vitro availability.
ISSN:0031-7144