Use of intra-arterial chemotherapy in the treatment of malignant tumors in children

Transcatheter arterial chemotherapy has been perfected in the treatment of 66 patients with various severe malignant tumors. A total of 75 arterial cytostatic injections were made, out of them 57 were given in primary tumors and 18 in tumor metastases. The children's age ranged from 1 to 14 yea...

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Bibliographic Details
Published inVestnik Rossiĭskoĭ akademii medits︠i︡nskih nauk no. 4; p. 11
Main Authors Smirtiukov, S V, Poliaev, Iu A, Strykov, V A, Kovalev, V I, Goncharov, M Iu, Nikanorov, A Iu, Bukhny, A F
Format Journal Article
LanguageRussian
Published Russia (Federation) 1994
Subjects
Adolescent
Antineoplastic Agents - administration & dosage
Bone Neoplasms - drug therapy
Child
Child, Preschool
Humans
Infant
Infusions, Intra-Arterial
Kidney Neoplasms - drug therapy
Liver Neoplasms - drug therapy
Lymphoma, Non-Hodgkin - drug therapy
Neoplasms - drug therapy
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Summary:Transcatheter arterial chemotherapy has been perfected in the treatment of 66 patients with various severe malignant tumors. A total of 75 arterial cytostatic injections were made, out of them 57 were given in primary tumors and 18 in tumor metastases. The children's age ranged from 1 to 14 years. High arterial therapeutic doses in combination with extracorporeal blood purification by hemosorption in the treatment of hepatic metastases yielded 100% efficiency. Prolonged arterial chemotherapy for pulmonary metastases provided an excellent therapeutic effect. Thus, 75 arterial injections of cytostatics gave rise to 32% of complete remissions, 48% of partial remissions. There was no benefit in 20% of cases. Adverse reactions were absent.
ISSN:0869-6047