Middle molecules and tuberculosis activity in children and adolescents at the sanatorium stage of treatment

Medium-weight molecules (MWM) were measured in the plasma of 67 children and adolescents aged 11 to 17 years who were infected with and suffered from various types of tuberculosis. The highest values of MWM were found in patients with tuberculous exudative pleuritis and infiltrative pulmonary tuberc...

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Bibliographic Details
Published inProblemy tuberkuleza no. 4; p. 48
Main Authors Lozovskaia, M E, Korol', O I, Sokurov, V P, Sycheva, N F, Ostanko, L V
Format Journal Article
LanguageRussian
Published Russia (Federation) 1996
Subjects
Adolescent
Child
Female
Health Resorts
Humans
Male
Molecular Weight
Peptides - blood
Spectrophotometry, Ultraviolet
Tuberculosis, Lymph Node - blood
Tuberculosis, Lymph Node - diagnosis
Tuberculosis, Lymph Node - rehabilitation
Tuberculosis, Pleural - blood
Tuberculosis, Pleural - diagnosis
Tuberculosis, Pleural - rehabilitation
Tuberculosis, Pulmonary - blood
Tuberculosis, Pulmonary - diagnosis
Tuberculosis, Pulmonary - rehabilitation
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Summary:Medium-weight molecules (MWM) were measured in the plasma of 67 children and adolescents aged 11 to 17 years who were infected with and suffered from various types of tuberculosis. The highest values of MWM were found in patients with tuberculous exudative pleuritis and infiltrative pulmonary tuberculosis. During treatment, there was a significant reduction in the mean levels of MWM in 20 follow-up patients. It is concluded that it is expedient to employ this test to detect insidious tuberculosis activity during sanatorium treatment and to use it as a criterion for therapeutical efficiency.
ISSN:0032-9533