Effect of detergents on the hydroxylation of indolyl-3-acetic acid by an Aspergillus niger culture

A possibility to increase the hydroxylating activity of Aspergillus niger IBFM F-212 under the action of detergents was studied during transformation of indolyl-3-acetic acid (IAA). The following non-ionogenic surface-active compounds were mainly used: Tweens, Spans, polyethyleneglycol (PEG-400). Th...

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Bibliographic Details
Published inMikrobiologija (Moskva. 1932) Vol. 49; no. 4; p. 546
Main Authors Baklashova, T G, Koshcheenko, K A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1980
Subjects
Aspergillus - enzymology
Aspergillus niger - drug effects
Biotransformation - drug effects
Detergents - pharmacology
Enzyme Activation - drug effects
Hydroxylation
Indoleacetic Acids - metabolism
Mixed Function Oxygenases - metabolism
Polyethylene Glycols - pharmacology
Polysorbates - pharmacology
Surface-Active Agents - pharmacology
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Summary:A possibility to increase the hydroxylating activity of Aspergillus niger IBFM F-212 under the action of detergents was studied during transformation of indolyl-3-acetic acid (IAA). The following non-ionogenic surface-active compounds were mainly used: Tweens, Spans, polyethyleneglycol (PEG-400). The effect of the detergents was studied at the stages of growth, transformation and preincubation. At the stage of growth, the best effect was produced by Tween-80. At the stages of transformation and preincubation, the hydroxylating activity increased 1.5 times under the action of a number of Spans and PEG-400. No total positive effect of the detergents on the enzyme activity was found at the stages of growth and transformation. The results suggest that the cellular permeability changes under the action of detergents and the hydroxylating activity of the culture increases as the result.
ISSN:0026-3656