Radioimmunological analysis in assessing the function of the hypothalamo-neurohypophyseal system in patients with hypothalamic syndromes

Assessment of vasopressin by radioimmunoassay has shown an increase in its blood concentration and a disturbed reaction of the vasopressinergic structures of the hypothalamus to metoclopramide, furosemide, insulin hypoglycemia, and exercise. Functional tests with the dopaminergic drug bromocriptine...

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Bibliographic Details
Published inMeditsinskaia radiologiia Vol. 36; no. 11; p. 37
Main Authors Slavnov, V N, Markov, V V, Rudichenko, V M
Format Journal Article
LanguageRussian
Published Russia (Federation) 1991
Subjects
Adolescent
Adult
Chronic Disease
Exercise Test
Humans
Hypothalamic Diseases - blood
Hypothalamic Diseases - physiopathology
Hypothalamo-Hypophyseal System - drug effects
Hypothalamo-Hypophyseal System - physiopathology
Middle Aged
Pituitary Gland, Posterior - drug effects
Pituitary Gland, Posterior - physiopathology
Radioimmunoassay - methods
Syndrome
Time Factors
Vasopressins - blood
Vasopressins - drug effects
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Summary:Assessment of vasopressin by radioimmunoassay has shown an increase in its blood concentration and a disturbed reaction of the vasopressinergic structures of the hypothalamus to metoclopramide, furosemide, insulin hypoglycemia, and exercise. Functional tests with the dopaminergic drug bromocriptine and antiserotoninergic drug cyproheptadine help to make an individual choice of the most effective drug for therapy of the hypothalamic syndrome of neuroendocrine-metabolic type. The patients can be divided into sensitive to either the first or the second drug of both which is important for adequate pathogenetic therapy.
ISSN:0025-8334