Laser therapy of villous rectocolonic tumors. Evaluation of results by multivariate analysis

One hundred and twenty-four patients (mean age: 70 years) with a villous tumour of the rectum (n = 98) or the colon (n = 26) were treated by laser therapy from 1985 to 1991. Initial complete eradication was obtained in 93.5% of cases with a median time of 16 months. Using multivariate analysis, the...

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Published inGastroentérologie clinique et biologique Vol. 17; no. 12; p. 938
Main Authors Ruget, O, Burtin, P, Ben Bouali, A K, D'Aubigny, N, Boyer, J
Format Journal Article
LanguageFrench
Published France 1993
Subjects
Adenoma, Villous - surgery
Adult
Aged
Aged, 80 and over
Colonic Neoplasms - surgery
Female
Follow-Up Studies
Humans
Laser Therapy - methods
Male
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local
Postoperative Complications
Rectal Neoplasms - surgery
Treatment Failure
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Summary:One hundred and twenty-four patients (mean age: 70 years) with a villous tumour of the rectum (n = 98) or the colon (n = 26) were treated by laser therapy from 1985 to 1991. Initial complete eradication was obtained in 93.5% of cases with a median time of 16 months. Using multivariate analysis, the tumor size (> 4 cm) only was predictive of eradication (P < 0.001). At 6 and 12 months, the actuarial eradication rates were 91 and 98% for small tumours versus 45 and 74% for larger tumours respectively. The actuarial recurrence rates were 10.5, 23, and 37% at 6, 12 and 24 months, and no longer increased after 3 years. No predictive factor of recurrence was isolated by multivariate analysis. Seven complications (5.6%) and 4 malignant transformations (3.4%) occurred. This study confirms the efficiency and low morbidity of laser therapy, especially in patients with small tumors, less than 4 cm in size.
ISSN:0399-8320