Effect of dekaris and sodium nucleinate on the blood antioxidant system of guinea pigs exposed to paprin inhalation

The changes of lipid peroxidation, thiol disulfide equilibrium, glucoso-6-phosphate dehydrogenase, catalase and superoxide dismutase activity under influence of immunostimulants during paprin inhalation were studied. Pro-oxidant effect of dekaris has been established. The conclusion on the necessity...

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Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 107; no. 4; p. 426
Main Authors Shleĭkin, A G, Chechura, A N, Shliakhetskiĭ, N S, Dzhangulova, N E, Sokolova, E A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.04.1989
Subjects
Adjuvants, Immunologic - therapeutic use
Administration, Inhalation
Animals
Antioxidants
Catalase - blood
Dietary Proteins
Erythrocytes - drug effects
Erythrocytes - enzymology
Glucosephosphate Dehydrogenase - blood
Guinea Pigs
Levamisole - therapeutic use
Lipid Peroxidation - drug effects
Male
Nucleic Acids - therapeutic use
Oxidation-Reduction
Proteins - toxicity
RNA, Fungal - therapeutic use
Sulfhydryl Compounds - blood
Superoxide Dismutase - blood
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Summary:The changes of lipid peroxidation, thiol disulfide equilibrium, glucoso-6-phosphate dehydrogenase, catalase and superoxide dismutase activity under influence of immunostimulants during paprin inhalation were studied. Pro-oxidant effect of dekaris has been established. The conclusion on the necessity to estimate the level of antioxidant system under immunocorrection has been made.
ISSN:0365-9615