The effect of a suspension of brain cells from mice of varying age on the growth of tumors, transplanted under the capsule

Antitumour activity of cerebral cells at different stages of ontogenesis (embryonic, new-born, adult) has been studied. Researches have been carried out at killer-activity patterns in vitro with target-cells and tumour transplantation under mice kidney's capsule in vivo. It has been established...

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Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 115; no. 2; p. 195
Main Authors Lisianyĭ, N I, Romodanov, A P, Oleĭnik, G M, Markova, O V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.02.1993
Subjects
Age Factors
Animals
Brain - cytology
Brain - immunology
Cell Division
Cells, Cultured
Kidney
Mice
Mice, Inbred CBA
Neoplasm Transplantation
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Summary:Antitumour activity of cerebral cells at different stages of ontogenesis (embryonic, new-born, adult) has been studied. Researches have been carried out at killer-activity patterns in vitro with target-cells and tumour transplantation under mice kidney's capsule in vivo. It has been established that mice cerebral cells' suspension can decrease the tumour transplants' growth under kidney's capsule. Antiproliferative activity of embryonic and new-born mice cerebral cells was much higher than adult one. The kidney and liver new-born mice cells had no antiproliferative activity at all.
ISSN:0365-9615