Stimulation of wound healing with thrombocyte growth factors in treatment of chronic unhealed wounds

The management of chronic wounds remains a challenge for various medical and surgical specialties. General strategies include local wound care, surgery, skin grafting, debridement, and vascular reconstruction. However, many wounds remain resistant to conventional therapies. Because platelet factors...

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Bibliographic Details
Published inHandchirurgie, Mikrochirurgie, plastische Chirurgie Vol. 26; no. 3; p. 160
Main Authors Flesch, I, Köveker, G, Tolksdorf-Kremmer, A, Coerper, S, Becker, H D
Format Journal Article
LanguageGerman
Published Germany 01.05.1994
Subjects
Administration, Topical
Adult
Aged
Aged, 80 and over
Chronic Disease
Diabetic Foot - therapy
Female
Humans
Male
Middle Aged
Platelet-Derived Growth Factor - administration & dosage
Transforming Growth Factor alpha - administration & dosage
Varicose Ulcer - therapy
Wound Healing - drug effects
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Summary:The management of chronic wounds remains a challenge for various medical and surgical specialties. General strategies include local wound care, surgery, skin grafting, debridement, and vascular reconstruction. However, many wounds remain resistant to conventional therapies. Because platelet factors are important in the normal mechanism of wound healing, we report on the topical application of platelet-derived growth factor. Our initial results suggest that the topical application may stimulate and promote healing of chronic wounds.
ISSN:0722-1819