Clinical experience with cefotiam infusions in chronic sinusitis and otitis media

Clinical efficacy and safety of cefotiam were studied. Twelve patients with chronic sinusitis and 14 patients with chronic otitis media were intravenously given cefotiam in daily doses of 2 g for 7 to 10 days. In chronic sinusitis, clinical responses were excellent in 6 patients, good in 3 and fair...

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Bibliographic Details
Published inJapanese journal of antibiotics Vol. 36; no. 10; p. 2675
Main Authors Futaki, T, Oda, M
Format Journal Article
LanguageJapanese
Published Japan 01.10.1983
Subjects
Adolescent
Adult
Aged
Cefotaxime - administration & dosage
Cefotaxime - adverse effects
Cefotaxime - analogs & derivatives
Cefotiam
Child
Chronic Disease
Drug Evaluation
Female
Humans
Infusions, Parenteral
Male
Middle Aged
Otitis Media - drug therapy
Otitis Media - microbiology
Sinusitis - drug therapy
Sinusitis - microbiology
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Summary:Clinical efficacy and safety of cefotiam were studied. Twelve patients with chronic sinusitis and 14 patients with chronic otitis media were intravenously given cefotiam in daily doses of 2 g for 7 to 10 days. In chronic sinusitis, clinical responses were excellent in 6 patients, good in 3 and fair in 3, the rate of satisfactory clinical responses (excellent and good) being 75%. In chronic otitis media, the responses were excellent in 5, good in 4 and fair in 5, the rate of satisfactory clinical responses being 65%. As for side effects, eruption and abdominal pain were observed in 1 patient.
ISSN:0368-2781