Various biochemical indicators in prenatally alcoholized rats

A number of biochemical parameters have been determined which characterized the state of CNS and the structure of cell membranes in antenatally alcoholized animals. As compared with the control group the alcoholized animals had a significantly increased level of phosphatidyl inositol diphosphate in...

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Bibliographic Details
Published inVoprosy meditsinskoi khimii Vol. 35; no. 3; p. 33
Main Authors Mel'nik, E I, Tsirenina, M L, Ushakov, A N, Koltovaia, N A, Bobrova, O V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.05.1989
Subjects
Animals
Brain - enzymology
Brain - metabolism
Calcium - metabolism
Calpain - metabolism
Cell Membrane - metabolism
Cholesterol - metabolism
Female
Fetal Alcohol Spectrum Disorders - metabolism
Hydrolysis
Phosphatidylinositols - metabolism
Pregnancy
Rats
Serotonin - metabolism
Sialic Acids - metabolism
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Summary:A number of biochemical parameters have been determined which characterized the state of CNS and the structure of cell membranes in antenatally alcoholized animals. As compared with the control group the alcoholized animals had a significantly increased level of phosphatidyl inositol diphosphate in brain phospholipid fractions, while content of serotonin was reduced in their brain and increased in blood plasma; content of phosphatidyl serine and the cholesterol/phospholipids ratio were reduced in brain.
ISSN:0042-8809