Paraneoplastic encephalomyeloneuritis with anti-Hu antibodies and cancer of the rectum

We report the case of a 62-year-old man affected by anti-Hu-associated paraneoplastic encephalomyelitis. The underlying tumor was a neuroendocrine cancer of the rectum expressing Hu antigen. The neurologic presentation was limited to moderate sensitive neuropathy associated with two complex partial...

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Bibliographic Details
Published inRevue neurologique Vol. 153; no. 2; p. 135
Main Authors de Toffol, B, Uchuya, M, Michalak, S, Corcia, P, Hommet, C, Autret, A
Format Journal Article
LanguageFrench
Published France 01.03.1997
Subjects
Antibodies - analysis
Encephalomyelitis - etiology
Encephalomyelitis - immunology
Humans
Male
Middle Aged
Neuritis - etiology
Neuritis - immunology
Neuroendocrine Tumors - diagnosis
Neurons - immunology
Paraneoplastic Syndromes
Rectal Neoplasms - diagnosis
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Summary:We report the case of a 62-year-old man affected by anti-Hu-associated paraneoplastic encephalomyelitis. The underlying tumor was a neuroendocrine cancer of the rectum expressing Hu antigen. The neurologic presentation was limited to moderate sensitive neuropathy associated with two complex partial seizures (dreamy state) without any further signs of limbic encephalopathy. A paraneoplastic etiology should be considered in patients with moderate symptomatology. Paraneoplastic encephalomyelitis with anti-Hu antibodies is not always associated with small-cell lung cancer.
ISSN:0035-3787