Functional and morphological features of vitreoretinal proliferation after penetrating wounds of eye complicated by hemophthalmos (immunohistochemical and electron microscopy study)

Comprehensive (optic, electron, and fluorescent microscopy) morphological analysis of vitreous fragments removed in vitrectomy after penetrating wounds of the eye complicated by hemophthalmia showed that blood and damaged cells of pigment-free ciliary epithelium and the glia play an important role i...

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Bibliographic Details
Published inVestnik oftal'mologii Vol. 114; no. 6; p. 10
Main Authors Khoroshilova-Maslova, I P, Andreeva, L D, Bykov, V P, Chichua, G A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.1998
Subjects
Ciliary Body - injuries
Ciliary Body - metabolism
Ciliary Body - ultrastructure
Epithelium - immunology
Epithelium - metabolism
Epithelium - ultrastructure
Eye Hemorrhage - complications
Eye Hemorrhage - immunology
Eye Hemorrhage - pathology
Eye Injuries, Penetrating - complications
Eye Injuries, Penetrating - immunology
Eye Injuries, Penetrating - pathology
Fluorescent Antibody Technique
Follow-Up Studies
HLA-DR Antigens - biosynthesis
Humans
Immunoglobulin A - biosynthesis
Immunoglobulin G - biosynthesis
Microscopy, Fluorescence
Retina - injuries
Retina - metabolism
Retina - ultrastructure
Retinal Ganglion Cells - immunology
Retinal Ganglion Cells - metabolism
Retinal Ganglion Cells - ultrastructure
Rupture
Sclera - injuries
Vitreoretinopathy, Proliferative - etiology
Vitreoretinopathy, Proliferative - immunology
Vitreoretinopathy, Proliferative - pathology
Vitreous Body - injuries
Vitreous Body - metabolism
Vitreous Body - ultrastructure
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Summary:Comprehensive (optic, electron, and fluorescent microscopy) morphological analysis of vitreous fragments removed in vitrectomy after penetrating wounds of the eye complicated by hemophthalmia showed that blood and damaged cells of pigment-free ciliary epithelium and the glia play an important role in the development of proliferative processes in the ophthalmic cavity. Immunohistochemical studies revealed active expression of immunoglobulins A and G and of HLA-DR antigen on immunocompetent cells and abnormal expression of HLA-DR in pigment-free ciliary epithelium and the glia, confirming the autoimmune origin of inflammatory disorders.
ISSN:0042-465X