Neurocysticercosis treated with praziquantel. Long-term follow-up of a case

The Authors report a case of neurocysticercosis treated with praziquantel and ventriculoperitoneal shunt. The patient presented, at CAT, multiple intracranial calcifications and cysts located in the cerebral parenchyma, ventricular system and subarachnoid cisterns. Praziquantel was orally administer...

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Bibliographic Details
Published inJournal of neurosurgical sciences Vol. 35; no. 3; pp. 157 - 160
Main Authors Mancuso, P, Chiaramonte, I, Tropea, R
Format Journal Article
LanguageEnglish
Published Italy 01.07.1991
Subjects
Brain Diseases - diagnostic imaging
Brain Diseases - drug therapy
Brain Diseases - surgery
Cerebrospinal Fluid Shunts
Cysticercosis - diagnostic imaging
Cysticercosis - drug therapy
Cysticercosis - surgery
Drug Administration Schedule
Female
Follow-Up Studies
Humans
Middle Aged
Peritoneal Cavity
Praziquantel - administration & dosage
Praziquantel - therapeutic use
Tomography, X-Ray Computed
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Summary:The Authors report a case of neurocysticercosis treated with praziquantel and ventriculoperitoneal shunt. The patient presented, at CAT, multiple intracranial calcifications and cysts located in the cerebral parenchyma, ventricular system and subarachnoid cisterns. Praziquantel was orally administered at a daily dosage of 50 mg/kg. Two 15 day cycles of therapy were administered with an interval of one month between them. No significant side effects were observed during the treatment. Serial follow-up CAT scans demonstrated a gradual decrease in size and, finally, total disappearance of the cystic lesions. No neurological disfunction was observed at the last follow-up examination 4 years after treatment.
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ISSN:0390-5616