Effects of isoptin and obsidan on the coronary blood flow and tactics in anti-angina therapy of patients with ischemic heart disease

Single intravenous doses of isoptin (10 mg) and obsidan (5 mg) were tested for their effects on hemodynamic and coronary blood flow parameters in 35 patients with coronary heart disease and functional classes II-III angina pectoris of effort. In most cases, hemodynamic and coronary blood flow respon...

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Bibliographic Details
Published inKardiologiia Vol. 28; no. 10; p. 36
Main Authors Vakhliev, V D, Bogatyrev, I V, Uchaĭkina, L V, Syrkin, A L
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.10.1988
Subjects
Adult
Angina Pectoris - drug therapy
Angina Pectoris - physiopathology
Calcium Channel Blockers - administration & dosage
Calcium Channel Blockers - therapeutic use
Clinical Trials as Topic
Coronary Circulation - drug effects
Hemodynamics - drug effects
Humans
Infusions, Intravenous
Male
Middle Aged
Propranolol - administration & dosage
Propranolol - therapeutic use
Verapamil - therapeutic use
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Summary:Single intravenous doses of isoptin (10 mg) and obsidan (5 mg) were tested for their effects on hemodynamic and coronary blood flow parameters in 35 patients with coronary heart disease and functional classes II-III angina pectoris of effort. In most cases, hemodynamic and coronary blood flow responses to the drug administered were found to be identical. It was concluded that isoptin was effective as an antianginal agent in eukinetic hemodynamics, obsidan, in hyperkinetic one.
ISSN:0022-9040