Sleep apnea in myasthenia gravis

19 middle-aged patients with myasthenia gravis (MG) and 10 age-matched controls underwent overnight polysomnography and neuropsychological testing, in order to assess the frequency, degree, type and risk factors of sleep apneas in MG and to show their influence on sleep profile and neuropsychologica...

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Bibliographic Details
Published inWiener medizinische Wochenschrift Vol. 146; no. 9-10; p. 209
Main Authors Stepansky, R, Weber, G, Zeitlhofer, J
Format Journal Article
LanguageGerman
Published Austria 1996
Subjects
Adult
Arousal - physiology
Female
Humans
Male
Mental Recall - physiology
Middle Aged
Myasthenia Gravis - diagnosis
Myasthenia Gravis - physiopathology
Neurologic Examination
Neuropsychological Tests
Oxygen - blood
Polysomnography
Risk Factors
Sleep Apnea Syndromes - diagnosis
Sleep Apnea Syndromes - physiopathology
Sleep Stages - physiology
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Summary:19 middle-aged patients with myasthenia gravis (MG) and 10 age-matched controls underwent overnight polysomnography and neuropsychological testing, in order to assess the frequency, degree, type and risk factors of sleep apneas in MG and to show their influence on sleep profile and neuropsychological variables. We observed in 60% of the myasthenics, low grade central type of sleep apneas and hypopneas with resulting oxygen desaturations, occasionally occurring during REM-sleep without influence on sleep profile and vigilance but resulting in significant memory impairment. The only found risk factor for the development of sleep apneas was age.
ISSN:0043-5341