Primary septicemias in pediatric patients. Hospital Infantil de la Paz (1990-1993)

Septicemias comprise more than one third of nosocomial infections in children. Their risk factors are related with the exposition time, therefore they are evaluated in relationship to it. Prospective observational study along 4 years in surgical children and in those entered in the Internal Medicine...

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Bibliographic Details
Published inMedicina clínica Vol. 111; no. 20; p. 765
Main Authors Casanova, J F, Herruzo, R, Rosell, I, de Miguel, M
Format Journal Article
LanguageSpanish
Published Spain 12.12.1998
Subjects
Child, Preschool
Cross Infection - epidemiology
Cross Infection - etiology
Female
Hospitals, Pediatric - statistics & numerical data
Humans
Incidence
Infant
Male
Prospective Studies
Risk Factors
Sepsis - epidemiology
Sepsis - etiology
Spain - epidemiology
Survival Analysis
Time Factors
Spain
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Summary:Septicemias comprise more than one third of nosocomial infections in children. Their risk factors are related with the exposition time, therefore they are evaluated in relationship to it. Prospective observational study along 4 years in surgical children and in those entered in the Internal Medicine Unit patients of a children Hospital, with stays higher than two days. Data were collected from admission to discharge. Bivariant analysis of stay time until infection with Wilcoxon-Gehan test, followed by Cox regression with time interaction terms for the risk factors that did not fulfill the requisite of proportional risks. 4,098 children were studied. 3.8% suffered primary septicemia and more than one half had coagulase-negative staphylococci. Cox regression showed the following risk factors: type of surgery, peripheral and central venous catheter, urinary catheterization, stay previous to surgery and duration of intervention. The protection factors were more than 3 days of antibiotherapy, age higher than 1 year and male sex. The factors with interaction with time were: stay previous to surgery, sex and duration of intervention. The stay previous to surgery, antibiotherapy reduction and duration of instrumentations are risk factors susceptible to be modified in order to reduce the incidence of infection in children. Protection by means of antibiotics requires to be evaluated through an ad hoc designed study.
ISSN:0025-7753