Successful delivery following continuous cytostatic therapy of a leukemic pregnant women

The authors report about a successful labour and delivery after pregnancy with chronic myeloid leukemia treated with hydroxyurea. The haematological state of the mother could be well balanced with this cytostatic drug. The fetus was in a good condition during the whole pregnancy. At term a healthy n...

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Bibliographic Details
Published inOrvosi hetilap Vol. 134; no. 10; p. 527
Main Authors Szántó, F, Kovács, L
Format Journal Article
LanguageHungarian
Published Hungary 07.03.1993
Subjects
Adult
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - therapeutic use
Dose-Response Relationship, Drug
Female
Humans
Hydroxyurea - administration & dosage
Hydroxyurea - therapeutic use
Infant, Newborn
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy
Pregnancy
Pregnancy Complications, Hematologic - drug therapy
Pregnancy Outcome
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Summary:The authors report about a successful labour and delivery after pregnancy with chronic myeloid leukemia treated with hydroxyurea. The haematological state of the mother could be well balanced with this cytostatic drug. The fetus was in a good condition during the whole pregnancy. At term a healthy newborn delivered with no signs of malformation or haematological disease. At a follow up visit 6 weeks after delivery the state of the mother and the newborn was satisfactory. The incidence of leukemia and pregnancy is rare. The creation of a central registry to pool experiences and data would help define optimum treatment regimens for this group of patients. A close cooperation among haematologist, obstetrician and pediatrician is emphasized.
ISSN:0030-6002