The role of oxygen radicals in the physiology and pathology of human sperm

Reactive oxygen species in low doses are necessary compound of sperm capacitation and hyperactivation. Superoxide anion, hydroxyl radical and hydrogen peroxide initiate sperm capacitation. The edding of antioxidant enzymes inhibits the spontaneous and induced sperm hyperactivation. The process of ca...

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Published inFiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Vol. 44; no. 5-6; pp. 118 - 125
Main Authors Man'kovs'ka, I M, Serebrovs'ka, Z O
Format Journal Article
LanguageUkrainian
Published Ukraine 1998
Subjects
Free Radicals - metabolism
Humans
Male
Reactive Oxygen Species - physiology
Sperm Capacitation - physiology
Sperm Motility - physiology
Spermatozoa - pathology
Spermatozoa - physiology
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Summary:Reactive oxygen species in low doses are necessary compound of sperm capacitation and hyperactivation. Superoxide anion, hydroxyl radical and hydrogen peroxide initiate sperm capacitation. The edding of antioxidant enzymes inhibits the spontaneous and induced sperm hyperactivation. The process of capacitation is accompanied with the superoxide anion production output by spermatozoa. High doses of reactive oxygen species block the sperm motility through the inhibition of ATP synthesis by the mitochondrial enzymes and cell membrane compounds injury.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
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ISSN:2522-9028