Clinical and histopathological examination of enucleated eyes with contusion ruptures of cornea after radial keratotomy

Histopathological (histological, histochemical, and morphometric) examinations of 8 enucleated eyes with contusion ruptures of the cornea 2-13 years after radial keratotomy showed two patterns of changes caused by contusion and peculiar reparative processes in the keratotomic incisions. A characteri...

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Published inVestnik oftal'mologii Vol. 114; no. 4; p. 3
Main Authors Khoroshilova-Maslova, I P, Andreeva, L D, Ilatovskaia, L V, Kuznetsova, I A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1998
Subjects
Adult
Cicatrix - pathology
Contusions - complications
Contusions - pathology
Cornea - pathology
Cornea - surgery
Corneal Injuries
Eye Enucleation
Eye Injuries - etiology
Eye Injuries - pathology
Female
Follow-Up Studies
Humans
Keratotomy, Radial
Male
Refractive Surgical Procedures
Rupture
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Summary:Histopathological (histological, histochemical, and morphometric) examinations of 8 enucleated eyes with contusion ruptures of the cornea 2-13 years after radial keratotomy showed two patterns of changes caused by contusion and peculiar reparative processes in the keratotomic incisions. A characteristic feature of contusion injury after radial keratotomy is combination of changes typical of contusion and an extensive perforating corneal wound after its rupture along the incisions. Reparative processes in the keratotomic incisions were regarded as incomplete cicatrization resultant from inhibition of keratoblastic activity after a low-traumatic operation. The structure of cicatrice after keratotomic incisions differed from that of corneal cicatrices after cut wounds. The cicatrice consisted of an epithelial plug and stromal par with picrinophilic amorphous filamentous material and individual keratocytes but no proteoglycanes or filamentous matrix. The length of cicatrice was 80-95% of intact cornea thickness. The structure of keratotomic cicatrice implies its insecurity and sensitivity to blunt injury, and therefore patients should be informed of the necessity to avoid injuries.
ISSN:0042-465X