Comparative anti-arrhythmia effectiveness of activators of body stress-limiting systems in patients with arrhythmia

The antiarrhythmic effects produced by activators of the body's stress-limiting systems were comparatively evaluated in patients with cardiac arrhythmias of ischemic and non-ischemic etiology. Acediprol, gidazepam, and befol were found to be beneficial in ventricular premature contraction when...

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Bibliographic Details
Published inKardiologiia Vol. 32; no. 4; p. 25
Main Authors Meerson, F Z, Skibitskiĭ, V V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.04.1992
Subjects
Adult
Aged
Angina Pectoris - physiopathology
Anti-Anxiety Agents
Anti-Arrhythmia Agents - therapeutic use
Arrhythmias, Cardiac - drug therapy
Arrhythmias, Cardiac - etiology
Arrhythmias, Cardiac - physiopathology
Benzamides - therapeutic use
Benzodiazepines
Benzodiazepinones - therapeutic use
Coronary Disease - physiopathology
Female
Humans
Male
Middle Aged
Morpholines - therapeutic use
Neurocirculatory Asthenia - physiopathology
Receptors, GABA-A - drug effects
Stress, Physiological - physiopathology
Valproic Acid - therapeutic use
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Summary:The antiarrhythmic effects produced by activators of the body's stress-limiting systems were comparatively evaluated in patients with cardiac arrhythmias of ischemic and non-ischemic etiology. Acediprol, gidazepam, and befol were found to be beneficial in ventricular premature contraction when psychoemotional stress was simulated, as evidenced by 24-hour monitoring. The most pronounced protective therapeutical effect of the drugs was observed in patients with arrhythmias of extracoronary origin and in individuals with a marked arrhythmogenic effect of stress. Gidazepam was shown to suppress the provocative arrhythmogenic effect of the stress test.
ISSN:0022-9040