Acid hydrolase activity and cyclic nucleotide contents in the rat heart during myocardial ischemia and postischemic reperfusion

• Published in: Biulleten' eksperimental'noi biologii i meditsiny Vol. 108; no. 7; p. 30
• Main Authors: Ivanova, T N, Ivanov, A I, Korovkin, B F, Losev, N I
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.07.1989
• Subjects: Acid Phosphatase - analysis; Animals; Caffeine - pharmacology; Cathepsin D - analysis; Coronary Disease - metabolism; Coronary Disease - pathology; Cyclic AMP - analysis; Cyclic GMP - analysis; Male; Myocardial Reperfusion; Myocardium - analysis; Myocardium - pathology; Rats; Time Factors

The acid phosphatase and cathepsin D activities and cAMP and cGMP levels in isolated perfused rat heart were investigated during various periods of ischaemic myocardial injury and postischaemic reperfusion. The effect of phosphodiesterase inhibitor--caffeine was also studied. Free acid hydrolases ac...