Two cases of heterologous transplantation with peripheral blood

The first two cases in Mexico of patients with hematological malignancies treated with heterologous peripheral blood stem cell transplantation are presented. The stem cells were mobilized in the siblings by means of filgrastim; in one case, the graft was obtained from an identical twin and in the ot...

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Bibliographic Details
Published inRevista de investigacion clinica Vol. 49; no. 1; pp. 41 - 45
Main Authors Gómez-Almaguer, D, Ruiz-Argüelles, G J, Piñeiro, L A, Ruiz-Argüelles, A
Format Journal Article
LanguageSpanish
Published Mexico 01.01.1997
Subjects
Adolescent
Adult
Hematopoietic Stem Cell Transplantation
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
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Summary:The first two cases in Mexico of patients with hematological malignancies treated with heterologous peripheral blood stem cell transplantation are presented. The stem cells were mobilized in the siblings by means of filgrastim; in one case, the graft was obtained from an identical twin and in the other from an HLA-identical sibling. In both instances the post-transplant aplasia lasted less than 15 years and the engraftment was complete. In the allogeneic transplantation, the graft versus host disease was treated with immunosuppression. The approximate cost of each of these procedures was 20000 U.S. dollars. The advantages of grafting heterologous peripheral blood stem cells instead of bone marrow cells are briefly discussed, focusing on economic aspects.
Bibliography:ObjectType-Article-2
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ISSN:0034-8376