The correction of the pathological changes in the neuroendocrine system in hyperlipoproteinogenic microangiopathy

Thymalin and alpha-tocopherol were studied for their effects on the morphofunctional status of the hypothalamopituitary neurosecretory system, thyroid, and adrenals in early atherogenesis. Correction of abnormal changes in the neuroendocrine organs restored lipid hemostasis, lowered the rate of lipi...

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Bibliographic Details
Published inPatologicheskaia fiziologiia i eksperimental'naia terapiia no. 2; p. 9
Main Authors Pozdniakov, O M, Kobozeva, L P, Michunskaia, A B, Khabarina, I Iu, Klimenko, E D
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.04.1997
Subjects
Adjuvants, Immunologic - therapeutic use
Animals
Antioxidants - therapeutic use
Arteriosclerosis - drug therapy
Arteriosclerosis - pathology
Diet, Atherogenic
Drug Evaluation, Preclinical
Hyperlipoproteinemias - drug therapy
Hyperlipoproteinemias - pathology
Male
Microcirculation - drug effects
Microcirculation - pathology
Neurosecretory Systems - drug effects
Neurosecretory Systems - pathology
Rabbits
Thymus Hormones - therapeutic use
Time Factors
Vitamin E - therapeutic use
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Summary:Thymalin and alpha-tocopherol were studied for their effects on the morphofunctional status of the hypothalamopituitary neurosecretory system, thyroid, and adrenals in early atherogenesis. Correction of abnormal changes in the neuroendocrine organs restored lipid hemostasis, lowered the rate of lipid peroxidation, and prevented the progression of atherosclerotic changes in the great arteries.
ISSN:0031-2991