Cortisol metabolism in hypertensive patients during the crisis period

The examination was conducted in 67 patients with Stage II essential hypertension, aged 29 to 60 years (13 males and 54 females). Cortisol metabolism was assessed on the basis of a study of daily urine excretions of tetrahydrocortisol, tetrahydrocortisone, cortisol, cortisone, 17-oxy-11-desoxycortis...

Full description

Saved in:
Bibliographic Details
Published inKardiologiia Vol. 16; no. 11; p. 136
Main Authors Shelygina, N M, Zaretskiĭ, M M, Panichkina, V I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.1976
Subjects
Adrenal Cortex - metabolism
Adrenal Glands - metabolism
Adult
Cortisone - urine
Female
Humans
Hydrocortisone - metabolism
Hydrocortisone - urine
Hypertension - metabolism
Male
Middle Aged
Tetrahydrocortisol - urine
Tetrahydrocortisone - urine
Online AccessGet more information

Cover

More Information
Summary:The examination was conducted in 67 patients with Stage II essential hypertension, aged 29 to 60 years (13 males and 54 females). Cortisol metabolism was assessed on the basis of a study of daily urine excretions of tetrahydrocortisol, tetrahydrocortisone, cortisol, cortisone, 17-oxy-11-desoxycortisol and of their ratio. It is found that in patients with Stage II essential hypertension, beyond the period of exacerbation, cortisol metabolism and the glucocorticoid function of the adrenal cortex are unchanged. During crises the gluococorticoid function of the adrenal cortex is activated, and some changes develop in cortisol metabolism. The severity of the crisis does not affect cortisol metabolism, but results in a growing total secretory activity of the adrenal cortex.
ISSN:0022-9040