Morphologic changes following experimental influenza virus infection and the therapeutic administration of flavonoids in aqueous extract

Influenza virus strain A/PR8/34(H1N1) and flavonoid aqueous extract with therapeutical function were administered by intranasal route. Pathological examinations were done three and ten days after administration to evaluate the morphological modifications established in the lung parenchyma. Results s...

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Bibliographic Details
Published inRevue roumaine de virologie (Bucharest, Romania : 1990) Vol. 45; no. 1-2; p. 39
Main Authors Petica, M, Crişan, I, Eşanu, V, Petrescu, A
Format Journal Article
LanguageFrench
Published Romania 01.01.1994
Subjects
Animals
Flavonoids - pharmacology
Male
Mice
Orthomyxoviridae Infections - pathology
Solutions
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Summary:Influenza virus strain A/PR8/34(H1N1) and flavonoid aqueous extract with therapeutical function were administered by intranasal route. Pathological examinations were done three and ten days after administration to evaluate the morphological modifications established in the lung parenchyma. Results showed that therapeutical administration of flavonoids had good effects on interstitial bronchopneumonia evolution till complete recovery. Flavonoid aqueous extract administered by intranasal route was well tolerated by the organism.
ISSN:1018-0532