The treatment of pneumonias in influenza using antioxidants

Lipid peroxidation (LPO) has been studied in patients with influenza complicated by pneumonia as shown by GPL and MDA serum levels of GPL and MDA. Acute period of the disease was characterized by a sharp rise in LPO products production, especially in seriously ill patients. Administration of alpha-t...

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Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 68; no. 11; p. 33
Main Authors Nagibina, M V, Neĭfakh, E A, Krylov, V F, Braginskiĭ, D M, Kulagina, M G
Format Journal Article
LanguageRussian
Published Russia (Federation) 1996
Subjects
Acid-Base Equilibrium - drug effects
Acute Disease
Adolescent
Adult
alpha-Tocopherol - analogs & derivatives
Antioxidants - therapeutic use
Butylated Hydroxytoluene - therapeutic use
Humans
Influenza, Human - blood
Influenza, Human - complications
Lipid Peroxidation - drug effects
Middle Aged
Pneumonia - blood
Pneumonia - drug therapy
Pneumonia - etiology
Time Factors
Tocopherols
Vitamin E - analogs & derivatives
Vitamin E - therapeutic use
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Summary:Lipid peroxidation (LPO) has been studied in patients with influenza complicated by pneumonia as shown by GPL and MDA serum levels of GPL and MDA. Acute period of the disease was characterized by a sharp rise in LPO products production, especially in seriously ill patients. Administration of alpha-tocopherol promoted a significant decrease of MDA and GPL levels and more apparent clinical response. Dibunol caused minimal changes in the disease clinical pictures and LPO activity.
ISSN:0040-3660