Hematopoietic changes during fractional large-field irradiation of dogs with a subsequent bone marrow autograft

After the course of fractional large field irradiation of large volumes of bone marrow is completed (a total dose of 54 Cy), autotransplantation from the nonirradiated area of bone marrow contributes to a quicker restoration of blood cells amount injured at early stages after irradiation. The comple...

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Bibliographic Details
Published inArkhiv anatomii, gistologii i embriologii Vol. 89; no. 11; p. 53
Main Authors Klestova, O V, Sil'chenko, N N, Stanzhevskaia, T I, Markochev, A B, Skripkina, N S
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.1985
Subjects
Animals
Bone Marrow - pathology
Bone Marrow - radiation effects
Bone Marrow Transplantation
Dogs
Female
Hematopoiesis - radiation effects
Male
Radiation Dosage
Radiation Injuries, Experimental - pathology
Radiation Injuries, Experimental - therapy
Time Factors
Transplantation, Autologous
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Summary:After the course of fractional large field irradiation of large volumes of bone marrow is completed (a total dose of 54 Cy), autotransplantation from the nonirradiated area of bone marrow contributes to a quicker restoration of blood cells amount injured at early stages after irradiation. The complete restoration of haemopoiesis is observed in a year, and in animals with automyelotransplantation--after a half of the year and remains at the same level for 3 years.
ISSN:0004-1947